What is Aranesp used to treat?
Aranesp may be used to treat a lower than normal number of red blood cells (anemia) if it is caused by: • Chronic kidney disease (you may or may not be on dialysis). Chemotherapy that will be used for at least two months after starting Aranesp. months. If you have a cancer that has a high chance of being cured.
How often should Aranesp be given?
Aranesp is given every 1 to 4 weeks, depending on the condition you are treating. You may also need to take blood pressure medication. Follow your doctor’s instructions very carefully. Aranesp is injected under the skin, or given as an infusion into a vein.
When should I take Aranesp?
Initiate Aranesp treatment when the hemoglobin level is less than 10 g/dL. If the hemoglobin level approaches or exceeds 11 g/dL, reduce or interrupt the dose of Aranesp.
Can Aranesp cause kidney failure?
Aranesp may sometimes cause or worsen high blood pressure, especially in patients with long-term kidney failure….Table 5. Adverse Reactions Occurring in ≥ 5% of Patients with CKD.
| Adverse Reaction | Patients Treated with Aranesp (n = 766) |
|---|---|
| Hypertension | 31% |
| Dyspnea | 17% |
| Peripheral edema | 17% |
| Cough | 12% |
Can anemia cause kidney failure?
Anemia can happen early in the course of kidney disease and grow worse as kidneys fail and can no longer make EPO.
How quickly does Aranesp work?
Aranesp® “tells” the cells in your bone marrow to grow into new red blood cells within your bloodstream. Under healthy circumstances, it takes your body time to produce red blood cells (about 26 days 3,4,5,6). Increases in hemoglobin may not be observed until 2-6 weeks after you start taking Aranesp®.
How safe is Aranesp?
Aranesp increases the risk of death, myocardial infarction, stroke, venous thromboembolism, and thrombosis of vascular access and tumor progression or recurrence. Aranesp can also lead to an increase in adverse cardiovascular events, hypertension, seizures, and severe anemia.
How fast does Aranesp work?
What is the last stage of anemia?
The last stage is iron deficiency anemia. It is characterized by a low hemoglobin concentration with small (microcytic), pale (hypochromic) RBCs. Symptoms include fatigue upon exertion, weakness, headaches, apathy, pallor, poor resistance to cold temperatures, low physical work capacity, and poor immune function.