What is ethylene responsive factor?
The ethylene signaling and response pathway includes Ethylene Response Factors (ERFs), which belong to the transcription factor family APETALA2/ERF. It is well known that ERFs regulate molecular response to pathogen attack by binding to sequences containing AGCCGCC motifs (the GCC box), a cis-acting element.
What are ERF family of transcription factors?
The ERF family is a large gene family of transcription factors and is part of the AP2/ERF superfamily, which also contains the AP2 and RAV families (Riechmann et al., 2000). The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding.
What are TFs in transcription?
Transcription factors (TFs) along with RNA splicing, siRNA and histone modifications regulate the translatome. TFs are identifiable through their expression of a specific DNA binding domain (DBD). TFs, via their DBD, recognize and bind to a particular sequence of DNA.
What is the difference between a transcription factor and a coactivator?
A coactivator is a type of transcriptional coregulator that binds to an activator (a transcription factor) to increase the rate of transcription of a gene or set of genes. The activator contains a DNA binding domain that binds either to a DNA promoter site or a specific DNA regulatory sequence called an enhancer.
How do I target my transcription factor?
Here, we discuss various ways to target transcription factors in cancer models: by modulating their expression or degradation, by blocking protein/protein interactions, by targeting the transcription factor itself to prevent its DNA binding either through a binding pocket or at the DNA-interacting site, some of these …
What is the function of ethylene?
Ethylene is regarded as a multifunctional phytohormone that regulates both growth, and senescence. It promotes or inhibits growth and senescence processes depending on its concentration, timing of application, and the plant species.
What is the difference between activator and coactivator?
As nouns the difference between activator and coactivator is that activator is one who, or that which, activates while coactivator is (genetics) any protein that binds to an activator as part of gene transcription.