Can you take Bactrim with Eliquis?
Interactions between your drugs No interactions were found between Eliquis and sulfamethoxazole / trimethoprim.
Can you take antibiotics with apixaban?
No interactions were found between amoxicillin / clavulanate and Eliquis.
Does Eliquis need renal dosing?
Apixaban (Eliquis) renal dosing was included as 2.5 mg orally twice daily if at least one criterion is met: serum creatinine 1.5 mg per dL (133 μmol per L) or more, age 80 years or older, or weight 60 kg (132 lb, 4 oz) or less.
What antibiotics should not be taken with Eliquis?
clarithromycin apixaban Clarithromycin may increase the blood levels of apixaban, which may result in a higher risk of bleeding complications. You may need more frequent monitoring by your doctor to safely use both medications.
Can you take Bactrim with blood thinners?
warfarin sulfamethoxazole Using warfarin together with sulfamethoxazole may increase the risk of bleeding, especially if you are elderly or have kidney or liver impairment. You may need more frequent monitoring of your prothrombin time or INR by your doctor to safely use both medications.
What drugs should not be taken with Bactrim?
Common medications that may interact with Bactrim include:
- anticonvulsants such as phenytoin.
- antidepressants, such as amitriptyline, amoxapine, and desipramine.
- cyclosporine.
- digoxin.
- anticoagulants (blood thinners), such as warfarin.
- blood pressure medications, such as captopril or enalapril.
- indomethacin.
- pyrimethamine.
What medications should you not take with apixaban?
Common medicines that can increase bleeding when taken with apixaban include:
- Aspirin or other products that contain aspirin.
- Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) such as Advil, Motrin and Aleve.
- Any medicine that contains heparin such as Lovenox, Innohep or Fragmin.
Can you give Eliquis in renal failure?
The use of all direct oral anticoagulants is not recommended in patients with creatinine clearance below 15 mL/min. Apixaban has the lowest fraction of renal excretion (27%) and is sometimes used in patients with CKD V (GFR < 15 mL/min/BSA) and end stage renal disease (ESRD).
Is Eliquis renally cleared?
In this study, the contribution of apixaban renal clearance to total clearance was 34 %. The average contribution of renal clearance across these two studies was approximately 27 %, supporting the statement in both the Eliquis® (apixaban) SmPC and USPI [2, 6].
What medications interact with apixaban?
Some products that may interact with this drug include: mifepristone, other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, “blood thinners” such as warfarin, enoxaparin), certain antidepressants (including SSRIs such as fluoxetine, SNRIs such as desvenlafaxine/venlafaxine).
Can you take Bactrim while on warfarin?
Indeed, Bactrim is the Sabretooth to warfarin’s Wolverine. You will probably reduce the warfarin dose by about 50% for patients starting Bactrim. In higher risk, more sensitive patients, you may even hold a dose of warfarin and then reduce it.
What is the correct dose of apixaban for impaired renal function?
Clarification for Apixaban Dosing in Patients with Impaired Renal Function. Apixaban (Eliquis) renal dosing was included as 2.5 mg orally twice daily if at least one criterion is met: serum creatinine 1.5 mg per dL (133 μmol per L) or more, age 80 years or older, or weight 60 kg (132 lb, 4 oz) or less.
What is the recommended Bactrim dosage regimen?
Bactrim Dosage Creatinine Clearance (mL/min) Recommended Dosage Regimen Above 30 Usual standard regimen 15–30 ½ the usual regimen Below 15 Use not recommended
How to reduce dose of Eliquis (apixaban)?
Reduce dose by 50%:For patients receiving ELIQUIS®(apixaban) doses of 5 mg or 10 mg twice daily,when ELIQUIS is coadministered with drugs that are combined P-gp and strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, or ritonavir). Clarithromycin Although clarithromycin is a combined P-gp and strong CYP3A4 inhibitor, pharmacokinetic data
How often can you take apixaban for DVT?
ELIQUIS®(apixaban) DOSING SUMMARY After 7 days, transition to 5 mg twice daily Treatment of DVT/PE E For all indications: Please see page 15 for additional dosage adjustment information on coadministration with combined P-glycoprotein (P-gp) and cytochrome P450 3A4 (CYP3A4) inhibitors. Indication Recommended dosing Prophylaxis of DVT,
