What does ATP8 do?
Function. The MT-ATP8 gene encodes a subunit of mitochondrial ATP synthase, located within the thylakoid membrane and the inner mitochondrial membrane. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation.
What gene codes for ATP synthase?
ATP5F1A Gene – ATP Synthase F1 Subunit Alpha This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation.
Is ATP A synthase?
The ATP synthase is a mitochondrial enzyme localized in the inner membrane, where it catalyzes the synthesis of ATP from ADP and phosphate, driven by a flux of protons across a gradient generated by electron transfer from the proton chemically positive to the negative side.
What are p side and n side in mitochondria?
As can be seen in Fig. 1(c), the inner side is the N side (negatively charged by electrons) and the outer side is the P side (positively charged by membrane-bound protons). The outermost sphere is the outer mitochondrial membrane (OMM). The space between the P side and the OMM is the intermembrane space (IMS).
What is ATPase function?
ATPases are a group of enzymes that catalyze the hydrolysis of a phosphate bond in adenosine triphosphate (ATP) to form adenosine diphosphate (ADP). They harness the energy released from the breakdown of the phosphate bond and utilize it to perform other cellular reactions.
What does the MT-ATP8 gene do?
The MT-ATP8 gene encodes a subunit of mitochondrial ATP synthase, located within the thylakoid membrane and the inner mitochondrial membrane. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation.
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Where is MT-ATP8 located in the plasma membrane?
As an A subunit, MT-ATP8 is contained within the non-catalytic, transmembrane F o portion of the complex, comprising the proton channel.