What percentage of spiculated breast masses are cancer?
For example, a spiculated (or stellate) lesion has a high positive predictive value for malignancy, often around 90%2, whereas a mass with a circumscribed contour most often indicates a benign lesion (e.g. fibroadenoma, cyst or hamartoma)3.
Does spiculated always mean cancer?
Although a spiculated mass is thought of as a classic finding of malignancy on mammography, ultrasound, and MRI, its differential diagnosis includes benign lesions.
What percent of spiculated masses are benign?
This is confirmed by this review of the first 8 years of screening in East Sussex where only 3.6% of masses with spiculation were benign at excision (24 out of 668), compared with 33.3% of masses without spiculation (102 out of 306).
What kind of breast cancer is Spiculated mass?
Our study shows that the presence of a spiculated mass is associated with the luminal A subtype of invasive breast cancer, and the status of Ki67 and HER2 may perhaps be the most significant factors affecting the visualization of a spiculated mass.
What does spiculated lump mean?
(SPIH-kyoo-LAY-ted …) A lump of tissue with spikes or points on the surface.
What does spiculated nodule mean?
The spiculation sign is the main feature to distinguish benign pulmonary nodules from malignant ones. It is defined as a radial and unbranched stripe shadow extending from the boundary of a pulmonary nodule to the surrounding pulmonary parenchyma.
Can benign tumors be spiculated?
Abstract. Spiculated breast lesions may be caused by both benign and malignant processes, including sclerosing adenosis, postsurgical scar, radial scar, tuberculosis (rare), posttraumatic oil cysts, infiltrating ductal carcinoma, ductal carcinoma in situ (rare), infiltrating lobular carcinoma, and tubular carcinoma.
Can DCIS be spiculated?
This pattern can be seen in infiltrating ductal or lobular carcinomas. It can also be seen in DCIS, although that is unusual. In addition to carcinoma, spiculated masses can be caused by radial scar, postoperative scarring, fat necrosis, desmoid tumor, hemorrhage, and abscess.
What does Spiculation mean?
Spiculation is a stellate distortion caused by the intrusion of breast cancer into surrounding tissue. Its existence is an important clue to characterizing malignant tumors. Many successful mammographic methods have been proposed to detect tumors with spiculation.
Can benign tumors be Spiculated?
What does a Spiculated nodule look like?
The margins of many cancers are uneven, look spiky and are described as “spiculated”. Most nodules that are not cancer have smooth or rounded margins or look like several rounded nodules together (also called “lobulated”). Density describes how compact a substance like bone or tissue appears on an image.
What does Spiculated Mass mean?
What is a spiculated mass on the breast?
Some studies have shown that a spiculated mass typically has at least 30 percent more progesterone receptors and estrogen receptors than normal breast tissue or non-spiculated lumps. If a spiculated mass is the cause of breast cancer, it should be discovered by performing a mammogram.
Is a spiculated mass always cancerous?
If a spiculated mass is the cause of breast cancer, it should be discovered by performing a mammogram. While usually cancerous, it is possible in rare cases for a spiculated mass to be benign, particularly in instances where there is scar tissue, granular tumors or the presence of foreign matter in the body.
What are spiculated lesions with microcalcifications in breast cancer?
Mammographically, such lesions are often similar, and only some can be differentiated on the basis of morphologic characteristics. Although microcalcifications are often associated with breast carcinoma, not all spiculated lesions with microcalcifications are malignant.
Is a spiculated mass on breast a red flag?
Fat necrosis, typically caused by trauma to the breast, often presents as a spiculated mass in its late stage, but somewhere around 50% of women with fat necrosis can’t recall a trauma to the breast. I am only one person. My spiculated mass did turn out to be cancer. Spiculated is a red flag.