What is Descemet membrane detachment?
Descemet membrane detachment (DMD) is a potential vision-threatening complication that occurs most commonly after cataract surgery. DMD has also been reported to occur in various other surgeries such as keratoplasty, iridectomy, vitrectomy, trabeculectomy, holmium laser sclerostomy, alkali burn, and viscocanalostomy.
What causes Descemet’s membrane detachment?
Descemet′s membrane detachment is a condition with a wide range of etiologies. The most common cause is a localized detachment occurring after cataract surgery. We report a case of vancomycin injection-induced Descemet′s membrane detachment as a complication following a routine cataract surgery and its management.
What happens to Descemet’s membrane as we age?
The thickness of Descemet’s membrane increases with aging. There is a decrease in corneal endothelial cell density that occurs with aging. The most precipitous decrease in cell density occurs in the first five years of life.
What is Descemet’s tear?
Descemet membrane detachment is a potentially devastating complication of cataract surgery. Small localized detachments are rarely problematic, however persistent extensive detachments can affect visual acuity. In severe cases penetrating keratoplasty may be required for restoration of vision.
What is Haab’s striae?
Haab striae are curvilinear breaks in Descemet’s membrane, resulting acutely from stretching of the cornea in primary congenital glaucoma. They are typically oriented horizontally or concentric to the limbus in contrast to Descemet’s tears, resulting from birth trauma, that are usually vertical or obliquely oriented.
Where is Descemet’s membrane?
the cornea
Descemet’s membrane (or the Descemet membrane) is the basement membrane that lies between the corneal proper substance, also called stroma, and the endothelial layer of the cornea.
Can Descemet’s membrane regenerate?
Descemet’s membrane is the basement membrane of the corneal endothelium. Descemet’s membrane modulates aqueous humor TGF beta and stromal fibrosis. Descemet’s membrane has poor potential to regenerate.
Can cornea repair itself?
The cornea can recover from minor injuries on its own. If it is scratched, healthy cells slide over quickly and patch the injury before it causes infection or affects vision. But if a scratch causes a deep injury to the cornea, it will take longer to heal.
What is Fincham test?
It is a test to determine whether a coloured halo originates from the lens (as in cataract) or from the cornea (as occurs in acute congestive glaucoma). A stenopaeic slit is passed across the pupil.
For what purpose is Descemet used?
The procedure is used to treat corneal edema in the setting of endothelial dystrophies (such as Fuchs corneal dystrophy and posterior polymorphous corneal dystrophy), pseudophakic bullous keratopathy, iridocorneal endothelial (ICE) syndrome, endothelial failure in the setting of prior intraocular surgery or of a …
What is Descemet’s membrane detachment?
Descemet’s membrane detachment is a complication occasionally faced after surgery. A detached Descemet’s membrane can be diagnosed on slit lamp examination as a clear optical space between the stroma and the Descemet’s membrane.
What is the success rate of Descemet membrane detachment reattachment?
We reported that in our study, 95.8% of Descemet membrane detachments reattached successfully after gas or air injection and 100% were reattached in cases involving the pupil in zone 1 by following the HELP algorithm. [8]
What is the mackool and Holtz classification for Descemet membrane detachment?
The management by Mackool and Holtz classification for Descemet membrane detachment was based on the length of detachment. They graded DMD as planar when it was less than 1mm and non-planar when more than 1mm.
How is detached Descemet’s membrane diagnosed?
A detached Descemet’s membrane can be diagnosed on slit lamp examination as a clear optical space between the stroma and the Descemet’s membrane. It is conventionally treated by injecting trypan blue dye into the anterior chamber to stain the Descemet’s membrane and to aid in visualization.