What is mesenchymal hamartoma?
Mesenchymal hamartoma is a benign tumor of the liver with a poorly understood pathogenesis. It is uncommon in older children, especially after 2 years of age. The signs and symptoms may be nonspecific; therefore, a high index of suspicion is required for diagnosis and treatment.
What is a hamartoma liver?
Mesenchymal hamartoma of the liver is a benign tumor of infancy characterized by an admixture of epithelial structures in a loose connective tissue stroma with fluid accumulation suggestive of lymphangiomatous channels.
Why is hamartoma not a tumor?
A hamartoma is a mostly benign, local malformation of cells that resembles a neoplasm of local tissue but is usually due to an overgrowth of multiple aberrant cells, with a basis in a systemic genetic condition, rather than a growth descended from a single mutated cell (monoclonality), as would typically define a …
How common is liver hemangioma?
A liver hemangioma (he-man-jee-O-muh) is a noncancerous (benign) mass in the liver made up of a tangle of blood vessels. Also known as hepatic hemangiomas or cavernous hemangiomas, these liver masses are common and are estimated to occur in up to 20% of the population.
Do hamartomas become malignant?
Hamartomas are usually solitary, well-demarcated nodules on roentgenogram. Multiple hamartoma are a rare entity and only 19 cases have been described in the world [20–22]. Slow growth is the norm for PH, malignancy is rare and only rare cases have been reported [23, 24].
Is hamartoma benign or malignant?
A benign (not cancer) growth made up of an abnormal mixture of cells and tissues normally found in the area of the body where the growth occurs.
What are hepatic mesenchymal hamartomas?
Hepatic mesenchymal hamartomas are uncommon benign hepatic lesions which are mostly seen in children under the age of 2. Some authors consider them to be developmental anomalies rather than cystic neoplasia 9,12.
What is the treatment for mesenchymal hamartoma of the liver?
DISCUSSION. Marsupialization is also proposed in cases not amenable to resection. [ 7] In previously reported cases of mesenchymal hamartoma occupying part of the liver, the tumors were successfully treated by surgical resection, and the remaining liver tissue provided adequate liver function.
Can a mesenchymal hamartoma show up on angiography?
While not being a standard diagnostic imaging modality of choice, angiography may show peripheral hypervascularity to the lesion with a septated avascular center 3-9. Mesenchymal hamartomas are benign lesions and are best treated by surgical resection, which usually results in cure 2.