How is aspirin made a level chemistry?
Aspirin is prepared by chemical synthesis from salicylic acid, through acetylation with acetic anhydride. The molecular weight of aspirin is 180.16g/mol. It is odourless, colourless to white crystals or crystalline powder.
What is the mechanism for making aspirin?
Aspirin can be made by reacting salicylic acid with acetic acid in the presence of an acid catalyst. The phenol group on the salicylic acid forms an ester with the carboxyl group on the acetic acid. However, this reaction is slow and has a relatively low yield.
How aspirin is prepared give equation?
Aspirin, a chemical called acetylsalicylic acid (ASA), is widely used worldwide as an anti-inflammatory and antipyretic drug. Formula and structure: the molecular formula for acetylsalicylic acid is C9H8O4 and the expanded formula is CH3COOC6H4COOH.
What is structure of aspirin?
C₉H₈O₄Aspirin / Formula
What type of reaction is synthesis of aspirin?
substitution reaction
The synthesis of aspirin is known in organic chemistry as an esterification reaction. This is a substitution reaction in which an alcohol (the –OH group in salicylic acid) reacts with acetic anhydride to form an ester, aspirin.
What is the purpose of synthesis of aspirin experiment?
The purpose of this lab was to synthesize Aspirin and measure the synthesized Aspirin’s purity. By calculating the theoretical yield based on the original amount of Salicylic acid, one could determine the actual yield percentage of the reaction.
What type of reaction is the synthesis of aspirin?
What is aspirin how it is prepared Class 12?
For the preparation of aspirin, salicylic acid is reacted with an excess of acetic anhydride. Small amount of strong acid is used as a catalyst in these reactions which enhances the speed of reaction acid used is phosphoric acid. Excess acetic acid will be extinguished with the addition of water.
Why is ethanol used in aspirin synthesis?
Ethanol has been chosen as the solvent because the polar nature of the hydroxyl group causes ethanol to dissolve many ionic compounds, moreover the ethanol molecule also has a non-polar end, and it will also dissolve non-polar substances. While cooling, crystallization takes place.
How to prepare salicylic acid for the preparation of aspirin?
EXPERIMENTAL SECTION 2.1 Preparation of Aspirin Care should be exercised when handling concentrated sulfuric acid and acetic anhydride. (1) Use a top-loading balance to weigh ca. 5.0 g of salicylic acid into a 100-mL conical flask. Record the mass of salicylic acid in the LRS.
What is the chemical formula for aspirin?
Chemical formula = C9H8O4 or CH3COOC6H4COOH or HC9H7O4 Aspirin is prepared by chemical synthesis from salicylic acid, through acetylation with acetic anhydride. The molecular weight of aspirin is 180.16g/mol. It is odourless, colourless to white crystals or crystalline powder.
How do you purify aspirin?
The solid aspirin product will be separated from the reaction mixture by suction filtration and further purified by recrystallization. A variety of techniques will then be used to assess the purity of the product. Start by creating a warm water bath: Fill a 250-mL Beaker with approximately 50-mL of water, heat it on a Heater/Stirrer to 70-80 oC.
What is the mechanism of action of aspirin?
Aspirin is an oral non-steroidal anti-inflammatory drug (NSAID) that is rapidly absorbed from the stomach and the small intestine. It is a non-selective NSAID as it irreversibly inhibits both cyclooxygenase (COX) enzymes involved in converting arachidonic acid to prostaglandins and thromboxane 3.