What is tocotrienol supplement used for?
People use tocotrienols for high cholesterol, scars, cancer, an inherited disorder called familial dysautonomia, a build-up of fat in the liver in people who drink little or no alcohol (nonalcoholic fatty liver disease or NAFLD), and many other conditions, but there is no good scientific evidence to support these uses.
What is the best source of tocotrienols?
Vegetable oils provide the best sources of these vitamin E forms, particularly palm oil and rice bran oil contain higher amounts of tocotrienols. Other sources of tocotrienols include grape fruit seed oil, oats, hazelnuts, maize, olive oil, buckthorn berry, rye, flax seed oil, poppy seed oil and sunflower oil.
Is vitamin E the same as tocotrienols?
The tocopherols are saturated forms of vitamin E, whereas the tocotrienols are unsaturated and possess an isoprenoid side chain. Some evidence suggests that human tissues can convert tocotrienols to tocopherols [2, 3]. Tocopherols consist of a chromanol ring and a 15-carbon tail.
Is tocotrienol better than vitamin E?
The chemistry of vitamin E The distinction between tocotrienols and tocopherols is chemical. Research has found that only tocopherol can correct vitamin E deficiency, which suggests that tocopherol is the form of vitamin E that the body needs to function efficiently.
Do tocotrienols help arthritis?
Several in vitro and in vivo studies have shown that the fraction of palm vitamin E and the tocotrienol fractions, which contain γ-tocotrienol and δ-tocotrienol, have anti-inflammatory activities, including the ability to inhibit inflammatory arthritis30,31.
Is tocotrienols good for hair loss?
In conclusion, this trial demonstrated that supplementation with tocotrienol capsules increases hair number in volunteers suffering from hair loss as compared to the placebo group.
What is the most powerful form of vitamin E?
alpha-tocopherol
Gamma-tocopherol is actually the major form of vitamin E ingested in the U.S. diet. It is not as well-known as alpha-tocopherol. The function of gamma-tocopherol is not entirely clear, but both forms (alpha and gamma) are potent antioxidants.
Why are tocotrienols better?
Tocotrienols are thought to have more potent antioxidant properties than α-tocopherol (Serbinova et al., 1991; Serbinova and Packer, 1994). The unsaturated side chain of tocotrienol allows for more efficient penetration into tissues that have saturated fatty layers such as the brain and liver (Suzuki et al., 1993).
Does tocotrienols help hair growth?
One study from 2010, for example, compared the results of people suffering from hair loss who took a supplement of tocotrienols with a control group which received a placebo supplement. After eight months, researchers saw a 34.5% increase in hair growth in the group who received tocotrienols.
Does vitamin E help joint pain?
Some laboratory and animal studies have also found that vitamin E may help to treat osteoarthritis by stimulating the growth of cartilage cells. Other studies have found that it has some anti-inflammatory properties.
Is vitamin E Good for autoimmune disease?
Regarding this, it is not surprising that vitamin E has a profound effect on the immune system by antioxidant activity. Studies suggest that vitamin E is associated with autoimmunity, as well as anti-inflammatory and immunomodulatory functions (15,16), especially in several inflammatory diseases (17).
What are tocotrienols?
Tocotrienols are chemicals in the vitamin E family. Vitamin E is a substance necessary for proper body and brain function. As with the other vitamin E chemicals, tocopherols, there are four types of tocotrienols found in nature: alpha, beta, gamma, and delta. Tocotrienols occur in the oils of rice bran, palm fruit, barley, and wheat germ.
What are the benefits of tocotrienols for high cholesterol?
Early research shows that taking tocotrienols for 3-4 months might reduce blood pressure problems in people with familial dysautonomia. But not all research agrees. High cholesterol. Research about the effects of tocotrienols on high cholesterol is conflicting.
Is tocotrienol cream safe to use?
When applied to the skin: There isn’t enough reliable information to know if tocotrienols are safe when applied to the skin. In some people, tocotrienol cream can cause mild itching. Pregnancy and breast-feeding: There isn’t enough reliable information to know if it is safe to use tocotrienols when pregnant or breast-feeding.
Is tocotrienols the vitamin E of the 21st century?
Aggarwal BB, Sundaram C, Prasad S, Kannappan R. Tocotrienols, the vitamin E of the 21st century: Its potential against cancer and other chronic diseases. Biochem Pharmacol 2010;80 (11):1613-1631. View abstract.