How long has Zonegran been on the market?
It was marketed by Élan in the United States starting in 2000 as Zonegran, before Élan transferred their interests in zonisamide to Eisai Co., Ltd. in 2004. Eisai also markets Zonegran in Asia (China, Taiwan, and fourteen others) and Europe (starting in Germany and the United Kingdom).
Does Zonegran cause memory loss?
The most common adverse reactions with ZONEGRAN (an incidence at least 4% greater than placebo) in controlled clinical trials and shown in descending order of frequency were somnolence, anorexia, dizziness, ataxia, agitation/irritability, and difficulty with memory and/or concentration.
When was zonisamide FDA approved?
Approval Date: 3/1/2000.
Why is Zonegran hazardous?
Because zonisamide can cause hematological complications, patients should contact their physician immediately if they develop a fever, sore throat, oral ulcers, or easy bruising. 6. As with other AEDs, patients should contact their physician if they intend to become pregnant or are pregnant during ZONEGRAN therapy.
Does zonisamide affect memory?
Zonisamide administered in a high, acute dose impairs the spatial memory. The drug given repeatedly disturbs spatial memory in the initial phase of the study. Zonisamide administered repeatedly impairs emotional memory.
Can zonisamide cause anger?
This medicine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away.
What does zonisamide do to the brain?
Zonisamide is used in combination with other medications to treat certain types of seizures. Zonisamide is in a class of medications called anticonvulsants. It works by decreasing abnormal electrical activity in the brain.
Is Keppra the same as zonisamide?
Zonegran (zonisamide) and Keppra (levetiracetam) are anticonvulsants used to treat seizures in patients with epilepsy. Side effects of Zonegran and Keppra that are similar include drowsiness, dizziness, tired feeling, and loss of appetite.
Is zonisamide similar to Topamax?
Zonisamide is similar to topiramate but has not yet been approved as an antimigraine medicine. In conclusion, results of this study suggest that zonisamide may be an effective agent for migraine prophylaxis. They could be compatible with previous studies of zonisamide treatment in migraine patients [21, 22].
What is the most important information I should know about Zonegran?
MEDICATION GUIDE ZONEGRAN (ZO-nuh-gran) (zonisamide) capsules What is the most important information I should know about ZONEGRAN? ZONEGRAN may cause serious side effects, including: 1. Serious skin rash that can cause death. 2. Serious allergic reactions that may affect different parts of the body. 3.
Is Zonegran approved in the US?
St. Michael, Barbados BB11005 ZONEGRAN® is a registered trademark of Dainippon Pharmaceutical Co. Ltd. and licensed exclusively to Concordia Pharmaceuticals Inc. This Medication Guide has been approved by the U.S. Food and Drug Administration Revised: April 2016
Is Zonegran use associated with central nervous system-related central nerve system related adverse events?
Use of Zonegran was frequently associated with central nervous system-related adverse events.
How do you take Zonegran?
Drink 6 to 8 glasses of water each day to prevent kidney stones while you are taking this medicine. Zonegran can be taken with or without food. Swallow the capsule whole. Do not crush, chew, open, or break it.