What is Susac syndrome caused by?
Causes. Susac syndrome is an autoimmune endotheliopathy, a disorder in which the body’s immune system mistakenly attacks the inside lining (endothelium) of the walls of the very tiny blood vessels that supply blood to the brain, retina, and inner ear. The exact, underlying reason why this occurs is unknown.
What are the symptoms of Susac syndrome?
What are the symptoms of Susac syndrome?
- Severe headache, often with vomiting.
- Confusion.
- Problems with thinking, such as short-term memory loss, slow thought processing and reduced ability to solve problems.
- Slurred speech.
- Walking difficulties.
- Changes in personality.
Can Susac syndrome be cured?
Although Susac syndrome is self-limiting and sometimes resolves spontaneously, early and aggressive treatment is recommended to prevent or minimize potential irreversible damage to the brain, retina, and inner ear. Usual treatment involves immunosuppression with high-dose glucocorticoids and IV immunoglobulin.
What is the treatment for Susac syndrome?
Treatment requires immunosuppression. High-dose corticosteroid therapy is the mainstay, but additional therapies such as intravenous immunoglobulin, mycophenolate mofetil, and cyclophosphamide are often necessary. Rituximab is the newest therapy to consider.
What autoimmune disease affects the blood vessels?
Vasculitis is an autoimmune disease that causes inflammation and narrowing of blood vessels (arteries, veins and capillaries). These vessels carry blood to and from the heart and the body’s organs. In severe cases, the condition can cause organ damage or death.
What is Marchiafava Bignami disease?
Marchiafava-Bignami disease (MBD) is a rare condition characterized by demyelination of the corpus callosum. It is seen most often in patients with chronic alcoholism.
Can an autoimmune disease cause high blood pressure?
Autoimmune diseases including systemic lupus erythematosus and rheumatoid arthritis are associated with an increased risk for hypertension and cardiovascular disease.