What is antibody SSA?
Anti-Ro/SSA antibodies are among the most frequently detected autoantibodies against extractable nuclear antigens and have been associated with systemic lupus erythematosus (SLE) and Sjögren’s syndrome (SS).
What are SSA and SSB antibodies?
INTRODUCTION. Anti‐SSA and ‐SSB antibodies are clinically important antinuclear antibody (ANA) in patients with systemic rheumatic diseases. These antibodies are found in Sjögren’s syndrome (SS), as well as other systemic autoimmune diseases (ADs), such as systemic lupus erythematosus (SLE), myositis, scleroderma, etc.
What is SSA 52 AB IgG?
SSA-52 (Ro52) and/or SSA-60 (Ro60) antibodies are associated with a diagnosis of Sjögren syndrome, systemic lupus erythematosus (SLE), and systemic sclerosis. SSA-52 antibody overlaps significantly with the major SSc-related antibodies.
What is SS A Elisa?
Enzyme immunoassay for the qualitative and quantitative determination of IgG antibodies against SS-A/Ro in human serum. SS-A/Ro-antibodies are directed against two distinct proteins, Ro52 and Ro60, which physiologically occur complexed with certain small hY-ribonucleic acids.
What is sjogrens AB Anti-SSA /- SS-B?
Anti-SS-A and anti-SS-B are autoantibodies that are associated with Sjögren’s syndrome. Anti-SSA and anti-SSB antibodies attack healthy glands that produce tears and saliva and can be present in several autoimmune conditions.
What is a normal SSA antibody level?
Table 1
| Case 1 | Normal range | |
|---|---|---|
| Anti-SSA/Ro52・Ro60 antibodies (anti-SSA/Ro antibodies) | 203 | < 10 U/mL |
| Anti-SSB/La antibodies | < 1.0 | < 10 U/mL |
| Anti-Scl-70 antibodies | 10.7 | < 10 U/mL |
| Rheumatoid factor (RF) | 16 | < 15 U/mL |
What is the difference between Sjogren’s A and Sjogren’s B?
SS-A antibodies are found in approximately 60-80% of Sjögren’s syndrome patients. SS-B antibodies are less common, being found in approximately 30-50% of Sjögren’s syndrome patients. SS-A antibodies thus occur commonly by themselves. However, it is very uncommon for SS-B antibodies to occur alone.
What antibodies are common in Sjogren’s syndrome?
The antibodies associated with Sjogren’s include anti-Ro (SS-A) and anti-La (SS-B) antibodies, rheumatoid factor, and antinuclear antibodies.