What are the Starling forces of capillary exchange?
Starling�s hypothesis states that the fluid movement due to filtration across the wall of a capillary is dependent on the balance between the hydrostatic pressure gradient and the oncotic pressure gradient across the capillary.
What is Transcapillary fluid exchange?
Chapter 7Transcapillary Fluid Exchange. The exchange of fluid between the blood and interstitium is dependent on the hydrostatic and colloid osmotic pressure gradients exerted across the microvasculature and by the permeability and hydraulic conductance characteristics of the capillary barrier.
What are the 3 ways of capillary exchange?
There are three mechanisms that facilitate capillary exchange: diffusion, transcytosis and bulk flow. Capillary dynamics are controlled by the four Starling forces. Oncotic pressure is a form of osmotic pressure exerted by proteins either in the blood plasma or interstitial fluid.
What is the formula to calculate Starling’s law?
The Starling equation, also known as the Frank–Starling heart law, was created in 1896 by Ernest Starling who was an English physicist:Jv=Kf([Pc-Pi])−σ[πc−2πi])
What happens when interstitial fluid accumulates?
Excessive accumulation of interstitial fluid is generally viewed as detrimental to tissue function because edema formation increases the diffusion distance for oxygen and other nutrients, which may compromise cellular metabolism in the swollen tissue.
What causes interstitial fluid?
Interstitial fluid is thought to be produced as a result of rhythmic alterations in arteriolar blood flow (vasomotion), which brings about movement of fluids from the blood through the unfenestrated capillaries into the interstitial space.
What are the primary mechanisms of capillary exchange?
What factors influence capillary exchange?
The rate of exchange, in either direction, is determined by physical factors: hydrostatic pressure, oncotic pressure, and the physical nature of the barrier separating the blood and the interstitium of the tissue (i.e., the permeability of the vessel wall).