What is meant by multidrug therapy?
In leprosy: Therapy. …can be killed rapidly, and multidrug therapy—the use of two or more antileprosy drugs in combination—prevents the development of drug-resistant strains.
What is the most effective multi drug antibiotic therapy for leprosy?
Antimicrobial chemotherapy The WHO recommended multidrug regimen of rifampicin, clofazimine, and dapsone has been used since 1982. It is highly effective, and more than 11.2 million patients have received it.
What are the drugs used for the treatment of leprosy?
Hansen’s disease is treated with a combination of antibiotics. Typically, 2 or 3 antibiotics are used at the same time. These are dapsone with rifampicin, and clofazimine is added for some types of the disease. This is called multidrug therapy.
What is Paucibacillary and Multibacillary leprosy?
Paucibacillary leprosy: 2 to 5 patches or lesions on the skin. Multibacillary leprosy: >5 patches or lesions on the skin. Recommended types of surveillance. Individual patient records at peripheral level for investigation and case-management.
How does MDT work for leprosy?
Multidrug therapy (MDT) is the treatment of choice for all leprosy patients. It entails the swallowing of a combination of anti-leprosy drugs on a daily basis, in the recommended doses for the recommended duration of treatment and according to the WHO leprosy classification.
WHO leprosy guidelines?
The currently recommended MDT regimen consists of medicines: dapsone, rifampicin and clofazimine. This treatment lasts six months for pauci-bacillary and 12 months for multi-bacillary cases. MDT kills the pathogen and cures the patient. Since 1981 WHO has provided MDT free of cost.
In which case of treatment MDT is applicable?
Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae) which mainly affects the skin and peripheral nerves. The treatment of leprosy has been revolutionized since the introduction of multidrug therapy (MDT) in 1981, following the recommendation of the World Health Organization (WHO).
What are types of leprosy?
There are 2 types of leprosy: tuberculoid leprosy and lepromatous leprosy. Tuberculoid leprosy is the less severe and less contagious form of the disease. Lepromatous leprosy is more severe and generalized.
What are the types of leprosy?
There are 2 types of leprosy: tuberculoid leprosy and lepromatous leprosy. Tuberculoid leprosy is the less severe and less contagious form of the disease. Lepromatous leprosy is more severe and generalized. It is also more contagious.
Which of the following is termed as leading drugs of treatment of leprosy?
Leprosy is curable with multidrug therapy. Treatment of paucibacillary leprosy is with the medications dapsone, rifampicin, and clofazimine for six months. Treatment for multibacillary leprosy uses the same medications for 12 months….
| Leprosy | |
|---|---|
| Medication | Rifampicin, dapsone, clofazimine |
| Frequency | 209,000 (2018) |
What is meant by Multibacillary?
Multibacillary (MB), or lepromatous, Hansen’s disease is characterized by generalized or diffuse involvement of the skin, a thickening of the peripheral nerves under microscopic examination, and has the potential to involve other organs, the eyes, nose, testes, and bone.
How can you distinguish between Multibacillary and Paucibacillary leprosy?
Paucibacillary patients are those who are skin smear negative and show no evidence of more advanced disease on biopsy. Multibacillary patients are those who are skin smear positive and/or have a biopsy indicating more advanced disease.