Is aristolochic acid toxic?
Side Effects, Toxicity AA, the toxic components of the Aristolochia species, are known to be nephrotoxic, carcinogenic, and mutagenic. A number of the Belgian patients have developed urothelial cancer as a result of exposure to the toxic aristolochic acids.
What products contain aristolochic acid?
Aristolochic acid is found primarily in the plant Aristolochia, but may also be present in other botanicals….Herb Danger – Aristolochic Acid Warning.
| Product Name | Responsible Firm |
|---|---|
| Fang Ji Stephania | Lotus Herbs Inc., LaPuente, CA (Distributor) |
| Mu Tong Clematis armandi | Lotus Herbs Inc., LaPuente, CA (Distributor) |
What herbs contain aristolochic acid?
Aristolochic acids are a group of acids found naturally in many types of plants known as Aristolochia (birthworts or pipevines) and some types of plants known as Asarum (wild ginger), which grow worldwide.
What is Chinese herb nephropathy?
Chinese herbs nephropathy (CHN) and Balkan endemic nephropathy (BEN) are chronic tubulointerstitial renal diseases associated with urothelial carcinoma. The clinical expression and pathological lesions observed at different stages of CHN and BEN are strikingly similar.
What is Balkan nephropathy?
Balkan endemic nephropathy (BEN) is a chronic tubulointerstitial disease associated with a high frequency of urothelial atypia, occasionally culminating in tumors of the renal pelvis and urethra.
What is Aristolochia used for?
Despite serious safety concerns, aristolochia is used to prevent seizures, increase sexual desire, boost the immune system, and start menstruation. It is also used to treat snakebite, intestinal pain, gallbladder pain, arthritis, gout, achy joints (rheumatism), eczema, weight loss, and wounds.
What herbs harm the kidneys?
The herbs listed by the National Kidney Foundation as having negative side effects on the renal system included alfalfa, aloe, bayberry, broom, buckthorn, capsicum, cascara, dandelion, ginger, ginseng, horsetail, licorice, ma huang, nettle, noni, pokeroot, rhubarb, senna, wormwood and yohimbe.
Can Chinese herbs cause kidney damage?
The incidence of kidney injury induced by Chinese herbal medicines is difficult to assess (7). However, in total, drug-related nephrotoxicity has been reported to contribute to about 26% of cases in patients with hospital-acquired AKI and 18% of cases in patients with community-acquired AKI globally.
What causes Balkan endemic nephropathy?
Evaluation of the hypothesis that Balkan endemic nephropathy is caused by drinking water exposure to contaminants leaching from Pliocene coal deposits. J Expo Sci Environ Epidemiol 2006; 16:515.
Is Aristolochia poisonous?
Aristolochia is UNSAFE. It contains aristolochic acid, which is toxic to the kidneys and causes cancer. Use of aristolochia can cause kidney damage leading to the need for kidney dialysis and kidney transplant. It also greatly increases the risk of bladder cancer and other urinary tract cancers.
Is Dutchman’s pipe poisonous to humans?
All members of Aristolochia macrophylla contain the natural substance aristolochic acid. This acid is toxic to humans.
