What is lichen planus pemphigoides?
Definition. Lichen planus pemphigoides can be best defined as an autoimmune dermatosis, the hallmarks of which are lichenoid and bullous skin lesions, which develop in the context of autoantibodies targeting type XVII collagen COL17.
How can you tell the difference between lichen planus and lichenoid reaction?
Abstract. Oral lichen planus (OLP) and oral lichenoid reaction (OLR) are clinically and histopathologically similar diseases. Whereas OLP is a consequence of T cell mediated autoinflammatory process to a still unknown antigen, OLR might be caused by drugs, dental restorative materials and dental plaque.
What is Hypertrophic Lichen Planus?
Hypertrophic lichen planus (HLP) is the second most common cutaneous variant of lichen planus. It is characterized as extremely pruritic, and thick hyperkeratotic plaques are seen primarily on the shins or dorsal aspect of the foot and may be covered by a fine adherent scale.
How is Lichen planus clinically?
Ulcerative lichen planus Ulcerative LP presents clinically as ill-defined, chronic, painful ulcers of the plantar surface. Perilesional skin may be erythematous and scaly. Walking may be impaired, toenails may be lost, and scarring may be present (Salavastru and Tiplica, 2010).
Is lichen planus premalignant?
Abstract. Oral lichen planus (OLP) is a common mucosal condition that is considered premalignant by some, although others argue that only lichenoid lesions with dysplasia are precancerous.
How can you tell the difference between lichen planus and candidiasis?
Background: Both Oral Lichen Planus (OLP) and oral candidiasis may have a polymorphic clinical appearance, but they have different etiologies; the former is classified as an immune-mediated inflammatory disease, whereas the latter is a condition of infectious origin frequently caused by the fungus Candida spp.
What is Koebner’s phenomenon in lichen planus?
What is the Koebner phenomenon? The Koebner phenomenon describes the appearance of new skin lesions of a pre-existing dermatosis on areas of cutaneous injury in otherwise healthy skin. It is also known as the Köbner phenomenon and isomorphic response.
What are Civatte bodies in lichen planus?
Who Described Civatte Bodies? Eosinophilic apoptotic (necrotic) keratinocytes in the lower epidermis and at the dermoepidermal junction are a feature of many interface dermatoses but are most reliably found in lichen planus. These structures are universally known as Civatte bodies.
What’s the difference between lichen sclerosus and lichen planus?
The main difference between the two conditions is that LP has a propensity to involve the mucous membranes including the mouth and vagina which are rarely affected in LS. First-line treatment for LS is a super-potent topical corticosteroid ointment which has a high response rate.
What is linear lichen planus?
Linear lichen planus (LLP) is a rare form of lichen planus, which is a condition that affects the skin and/or mouth. In LLP, specifically, affected people develop itchy, purple, flat-topped papules (bumps) in a linear distribution along the lines of Blaschko.